Dimitris K. Agrafiotis is responsible for architecture, design, implementation, operation, and support of IT services, and for establishing an encompassing informatics vision for innovation and strategic differentiation in company products. Earlier (2003-2013), he spent 10 years at Johnson & Johnson Pharmaceutical Research & Development as Vice President of Informatics and Research IT. Dr. Agrafiotis’s PhD — Theoretical Organic Chemistry (1998) is from Imperial College, London. He held postdoctoral fellowships at the University of California, Berkeley, and Harvard University, working with Nobel laureate E. J. Corey, regarded as the world’s greatest living chemist. In 1991, at Parke-Davis, he was Senior Scientist in the computer-aided drug design group; later moving to 3-Dimensional Pharmaceuticals (3DP) as a founding member of its scientific staff, responsible for building the company’s informatics and computational drug design capabilities. After very successful IPO and 3DP’s acquisition by Johnson & Johnson (2003), he became Senior Research Fellow and Team Leader of the Molecular Design & Informatics group (East Coast site), a position he held until 2006 when he became Global Head of Informatics and Research IT. His work spans computational life sciences and informatics is well documented (90 peer-reviewed publications and book chapters) and he holds 18 US patents. He delivers invited lectures, organizes national and international symposia, and serves on editorial boards of several prominent journals. A member of the Covance Science Council, he also serves as Adjunct Professor of Informatics (Indiana University School of Informatics) and the University of Athens School of Pharmacy. In 2012 he was elected Fellow of the Royal Society of Chemistry in recognition of his contributions to chemical and pharmaceutical research.